日本性感染症学会誌 Journal of Japanese Society for Sexually Transmitted Infections

Mycoplasma genitalium infection is an emerging global concern. The retrospective study analyzed 65 patients who underwent cobas TV/MG testing at a single institution between June 2023 and May 2024. The median age was 27 years, and 48 of the patients were female. A total of 13 patients visited on a weekday evening, and 17 visited on weekends or holidays. The primary symptoms prompting visits included urethritis (n=10), cystitis (n=20), cervicitis (n=27), and other conditions (n=13). Of the 65 patients, 12 tested positive for M. genitalium, and half of these were also co-infected with other sexually transmitted diseases (STDs). Of the 12 M. genitalium-positive patients, 9 were successfully treated with oral sitafloxacin (200 mg for 7 days). One patient, suspected of having a sitafloxacin-resistant M. genitalium infection, was subsequently treated with doxycycline (200 mg for 7 days). However, 17 patients did not reattend for follow-up, including 2 patients who had tested positive for M. genitalium. These findings highlight the risk of concurrent STD infections alongside M. genitalium infection and the significant challenge of low reattendance rate in STD clinical practice. Further efforts are required to address these issues.