日本性感染症学会誌 Journal of Japanese Society for Sexually Transmitted Infections

Online ISSN: 2434-2505　Print ISSN: 0917-0324
日本性感染症学会 Japanese Society for Sexually Transmitted Infections
〒162-0801東京都新宿区山吹町358-5アカデミーセンター Japanese Society for Sexually Transmitted Infections　Academy Center, 358-5 Yamabuki-cho, Shinju-ku, Tokyo 162-0801, Japan
Japanese Journal of Sexually Transmitted Infections 29(1): 109-111 (2018)
doi:10.24775/jjsti.29.1.109

症例報告症例報告

セフトリアキソン1 g単回投与後に核酸増幅法で淋菌陽性と判定した淋菌感染症5例Five cases positive for Neisseria gonorrhoeae by real-time polymerase chain reaction after 1 g intravenous ceftriaxone therapy

野口 武俊1，古賀 健一2，内田 千秋1,2，大塚 康文3，内浦 愛実3，財津 則子3Taketoshi Noguchi1, Kenichi Koga2, Chiaki Uchida1,2, Yasufumi Otuka3, Manami Uchiura3, Noriko Zaitsu3

1 あおぞらクリニック新宿院Aozora Clinic Shinjuku

2 あおぞらクリニック新橋院Aozora Clinic Shimbashi

3 あおぞらクリニック看護部Nursing Department, Aozora Clinic

受付日：2018年3月30日Received: March 30, 2018
受理日：2018年4月27日Accepted: April 27, 2018
発行日：2018年9月30日Published: September 30, 2018
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Currently, the first-line treatment for gonococcal infection is intravenous ceftriaxone, which has been demonstrated as effective for almost all patients. Between April 1, 2016, and March 31, 2017, real-time polymerase chain reaction (qPCR) or gonococcal antigen detection identified 459 patients with gonococcal urethritis and 122 with gonococcal pharyngitis in our hospital. All patients were treated intravenously with 1 g ceftriaxone. We report that five of these patients (two with gonococcal urethritis and three with gonococcal pharyngitis) showed Neisseria gonorrhoeae in the nucleic acid amplification after ceftriaxone treatment.

Key words: Neisseria gonorrhoeae; ceftriaxone; resistant

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